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Table 1 Functional and locational gene product categorization of Sortin2 hypersensitive ORFs.

From: Identification of cellular pathways affected by Sortin2, a synthetic compound that affects protein targeting to the vacuole in Saccharomyces cerevisiae

  Representation on dataset   Enrichment on dataset (-fold)
  Sortin2 Genome p-value  
FUNCTIONAL CATEGORY     
Cellular transport, transport facilities and transport routes 50.7 16.9 2.99 E-29 3.0
Protein fate (folding, modification, destination) 46.2 18.8 1.51 E-19 2.5
Biogenesis of cellular components 21.3 14 0.003 1.5
Interaction with the environment 12.9 7.55 0.004 1.7
LOCATIONAL CATEGORY     
Endosome 16.4 0.94 6.2 E-35 17.5
Golgi 13.9 2.57 1.0 E-13 5.4
Transport vesicles 11.4 2.29 1.1 E-10 5.0
Punctate composite 8.95 2.29 6.3 E-07 3.9
Vacuole 16.4 4.63 1.1 E-10 3.5
ER 15.9 9.1 0.0011 1.8
  1. Category representation of the abundance within Sortin2 hypersensitive (201 genes) and the Saccharomyces genome (6131 genes). P-value was calculated using hypergeometric distribution as statistical test. P-values < 0.0005 were considered as statistical significant.